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RSC Medicinal Chemistry|September 9, 2024
Chemical synthetic approaches to mimic the TRAIL: promising cancer therapeuticsAbdullah-Al Masum, Shin Aoki, Md Mahbubur Rahman, et al.
RSC Medicinal Chemistry|September 2, 2024
Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamidesHugo Kocek, Dominika Chalupská, Milan Dejmek, et al.
RSC Medicinal Chemistry|July 19, 2024
Leveraging bounded datapoints to classify molecular potency improvementsZachary Fralish, Paul Skaluba, Daniel Reker
RSC Medicinal Chemistry|July 19, 2024
Identification of AdipoRon analogues as novel activators of AMPK for the treatment of type 2 diabetesChao Lin, Geng Sun, Yi Li
RSC Medicinal Chemistry|July 19, 2024
Geometric deep learning-guided Suzuki reaction conditions assessment for applications in medicinal chemistryKenneth Atz, David F Nippa, Alex T Müller, et al.
RSC Medicinal Chemistry|July 19, 2024
Extension of multi-site analogue series with potent compounds using a bidirectional transformer-based chemical language modelHengwei Chen, Atsushi Yoshimori, Jürgen Bajorath
RSC Medicinal Chemistry|July 19, 2024
Rhodanine derived enethiols react to give 1,3-dithiolanes and mixed disulfidesJos J A G Kamps, Dong Zhang, Timothy D W Claridge, et al.
RSC Medicinal Chemistry|July 19, 2024
Inhibition of DXR in the MEP pathway with lipophilic N-alkoxyaryl FR900098 analogsDarean Bague, Ruiqin Wang, Dana Hodge, et al.
RSC Medicinal Chemistry|July 19, 2024
Discovery of first-in-class PROTACs targeting maternal embryonic leucine zipper kinase (MELK) for the treatment of Burkitt lymphomaYonghui Sun, Xiao Liu, Qiyu He, et al.
RSC Medicinal Chemistry|July 19, 2024
Synthesis of a new series of 4-pyrazolylquinolinones with apoptotic antiproliferative effects as dual EGFR/BRAFV600E inhibitorsLamya H Al-Wahaibi, Bahaa G M Youssif, Hesham A Abou-Zied, et al.
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