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RSC Medicinal Chemistry|September 8, 2025
Profile of NT-0527, a brain penetrant NLRP3 Inflammasome inhibitor suitable as an in vivo tool compound for neuroinflammatory disordersDavid Harrison, Andy Billinton, Mark G Bock, et al.RSC Medicinal Chemistry|September 8, 2025
Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD+ co-factor bindingRicky Wirawan, Matthias Frei, Anna Heider, et al.RSC Medicinal Chemistry|August 6, 2025
Toward routine utilisation of native mass spectrometry as an enabler of contemporary drug developmentLouise M Sternicki, Sally-Ann PoulsenRSC Medicinal Chemistry|July 31, 2025
Site-dependent modulation of antitumor activity and fluorescence in thieno[3,2-b]pyridin-5(4H)-onesDan-Bi Sung, Pham Van Thong, Jieun Yun, et al.RSC Medicinal Chemistry|July 28, 2025
EGFRAP: a predictive machine learning model for assessing small molecule activity against the epidermal growth factor receptorAshish Gupta, Amarinder S Thind, Rituraj PurohitRSC Medicinal Chemistry|August 27, 2021
Truncated S-MGBs: towards a parasite-specific and low aggregation chemotypeDaniel P Brooke, Leah M C McGee, Federica Giordani, et al.RSC Medicinal Chemistry|July 21, 2025
New quinazoline-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as inhibitors of EGFR: synthesis, anti-breast cancer evaluation and in silico studiesMahadev Dattatray Bandgar, Sampath Peddapelli, Ravikumar Kapavarapu, et al.RSC Medicinal Chemistry|July 4, 2025
New melatonin biphenyl-linked scaffold targeting colorectal cancer: design, synthesis, biological, and ADME-Tox modelling studiesMariluz Silva-García, Angie Herrera-Ramírez, Wilson Cardona-Galeano, et al.RSC Medicinal Chemistry|June 25, 2025
Structure-based design and evaluation of tyrosinase inhibitors targeting both human and mushroom isozymesSalvatore Mirabile, Giovanna Pitasi, Sonia Floris, et al.RSC Medicinal Chemistry|June 27, 2025
Lock and key: locked G quadruplexes could be the key to new modalities in nucleic acid therapeuticsNishant Nitinidhi Kulshreshtha, Philippe BarthélémyPageof 158