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RSC Medicinal Chemistry|December 10, 2025
Exploring pyrazolidinone and pyrazolidinedione scaffolds for Alzheimer's therapy: multitarget COX-2 inhibitors with anti-amyloid β, anti-tau, antioxidant, and neuroprotective activitiesMichael Emad, Reham Waheed, Zeinab Mostafa, et al.RSC Medicinal Chemistry|December 8, 2025
Diversifying the triquinazine scaffold of a Janus kinase inhibitorKleni Mulliri, Kris Meier, Johanna-Dorothea Feuchter, et al.RSC Medicinal Chemistry|November 26, 2025
Identification of spirodioxolane nsP2 helicase inhibitors with antialphaviral activityHans J Oh, John D Sears, Bose Muthu Ramalingam, et al.RSC Medicinal Chemistry|January 19, 2026
Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoesR Rajeshwari, V Duvauchelle, C Lindgren, et al.RSC Medicinal Chemistry|January 21, 2026
Parallels between the chloro and methoxy groups for potency optimizationDebora Chiodi, Yoshihiro IshiharaRSC Medicinal Chemistry|January 21, 2026
Sterically hindered catechol-derived Schiff bases: design, synthesis, SAR analysis and mechanisms of the antioxidant activityMaxim Gvozdev, Iveta Turomsha, Nikolai Osipovich, et al.RSC Medicinal Chemistry|January 21, 2026
Small molecule-mediated spatial targeting of mitochondria and the Golgi apparatus in cancer cellsPhanindra Kumar, Asima Sahu, Tripti Mishra, et al.RSC Medicinal Chemistry|January 8, 2026
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferaseIrene Georgiou, Colin Robinson, Sean N O'Byrne, et al.RSC Medicinal Chemistry|January 23, 2026
Kupffer cell M2-like polarization increases liver metastatic burden via the uptake of exosomal KRAS mutant protein from hypoxic colorectal carcinoma cellsYu You, Zhihao Feng, Jiao Lu, et al.RSC Medicinal Chemistry|January 12, 2026
The many facets of sustainability in medicinal chemistry: our personal experienceBianca Martinengo, Eleonora Diamanti, Elisa Uliassi, et al.Pageof 160