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RSC Medicinal Chemistry|December 25, 2025
Synthesis, antibacterial activity, and mechanistic characterization of novel 9-substituted berberine derivativesJiaying Tong, Huamao Yang, Yeying He, et al.
RSC Medicinal Chemistry|December 15, 2025
Discovery and optimization of pyrrolopyrimidines as highly potent, selective and brain-penetrant LRRK2 inhibitorsJeffrey M Axten, Xiao Ding, Luigi Piero Stasi, et al.
RSC Medicinal Chemistry|December 22, 2025
Discovery of novel progesterone-heterocyclic conjugates and their encapsulated polymeric nanoparticles as potential CDK8 inhibitors: lung cytotoxicity evaluation, gene expression, and molecular dockingYasmin Y Omar, Ghada F Elmasry, Dina S El-Kady, et al.
RSC Medicinal Chemistry|November 10, 2025
Data-driven assessment of bioisosteric replacements and their influence on off-target activity profilesPalle S Helmke, Julia Kandler, Sara Ilie, et al.
RSC Medicinal Chemistry|November 3, 2025
Sulfonation modification of peptides and their protective effect on angiotensin II-induced HK-2 cell injuryShuqian Chen, Shuqi He, Siyi Song, et al.
RSC Medicinal Chemistry|November 3, 2025
Designing halogen-free metal-phenolic imidazolium poly(ionic liquids) with multi-functional antibacterial, anti-inflammatory and cell proliferation properties for infected woundsDanni Wang, Xiaodong He, Yingcui Cai, et al.
RSC Medicinal Chemistry|July 7, 2025
Bioassay-guided isolation of hepatoprotective lignans from Vernonia cinerea: DeepSAT-driven structural elucidation and predictive mechanistic insights against drug-induced liver injuryMu Li, Meng-Ke Zhang, Xin Song, et al.
RSC Medicinal Chemistry|July 14, 2025
Exploration of hydrazine-based small molecules as metal chelators for KDM4 inhibitionAngus J Saxton, Jayden Sterling, Michael P Hamilton, et al.
RSC Medicinal Chemistry|July 14, 2025
Deciphering allosterism of an Escherichia coli hexuronate metabolism regulator: UxuRBeatriz C Almeida, Sean A Wirt, Kristala L J Prather, et al.
RSC Medicinal Chemistry|July 14, 2025
Design, synthesis, and apoptotic antiproliferative efficacy of new quinazoline/1,3,4-oxadiazole-2-thione derived EGFR/HER-2 dual inhibitors with anti-breast cancer activityHesham A M Gomaa, Mohamed E Shaker, Sami I Alzarea, et al.
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