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Science Immunology|August 21, 2021
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activationRahel Frick, Lene S Høydahl, Jan Petersen, et al.Science Immunology|May 22, 2021
Cutaneous innate immune tolerance is mediated by epigenetic control of MAP2K3 by HDAC8/9Yu Sawada, Teruaki Nakatsuji, Tatsuya Dokoshi, et al.Science Immunology|August 14, 2021
Single-cell analysis pinpoints distinct populations of cytotoxic CD4+ T cells and an IL-10+CD109+ TH2 cell population in nasal polypsJunjie Ma, Christopher A Tibbitt, Susanna Kumlien Georén, et al.Science Immunology|August 28, 2021
Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitisLaurent Calvier, Navid Manouchehri, Anastasia Sacharidou, et al.Science Immunology|November 19, 2021
Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg developmentClaudia Haftmann, Pascale Zwicky, Florian Ingelfinger, et al.Science Immunology|January 14, 2022
Tumors resurrect an embryonic vascular program to escape immunityElisabeth J M Huijbers, Kabir A Khan, Robert S Kerbel, et al.Science Immunology|January 14, 2022
FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expressionRicardo N Ramirez, Kaitavjeet Chowdhary, Juliette Leon, et al.Science Immunology|December 21, 2021
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammationNathalie Niyonzima, Jubayer Rahman, Natalia Kunz, et al.Science Immunology|December 3, 2021
In vivo genome-wide CRISPR screens identify SOCS1 as intrinsic checkpoint of CD4+ TH1 cell responseAurélien Sutra Del Galy, Silvia Menegatti, Jaime Fuentealba, et al.Science Immunology|December 3, 2021
Move over NAIP, DDX17 diversifies the NLRC4 inflammasomeKatherine C Barnett, Kaixin Liang, Jenny P-Y TingPageof 143