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Science Signaling|March 25, 2025
A sensitive biosensor of endogenous Gαi activity enables the accurate characterization of endogenous GPCR agonist responsesAlex Luebbers, Remi Janicot, Jingyi Zhao, et al.Science Signaling|March 26, 2025
Sustained chromosomal passenger complex activity preserves the pluripotency of human embryonic carcinoma cellsTakaaki Tsunematsu, Yasuhiro Mouri, Wenhua Shao, et al.Science Signaling|March 25, 2025
A lupus-derived autoantibody that binds to intracellular RNA activates cGAS-mediated tumor immunity and can deliver RNA into cellsXiaoyong Chen, Xiangjun Tang, Ying Xie, et al.Science Signaling|June 11, 2024
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stressVivian Chua, Melisa Lopez-Anton, Mizue Terai, et al.Science Signaling|June 4, 2024
Growth factor-dependent phosphorylation of Gαi shapes canonical signaling by G protein-coupled receptorsSuchismita Roy, Saptarshi Sinha, Ananta James Silas, et al.Science Signaling|June 18, 2024
Conformation- and activation-based BRET sensors differentially report on GPCR-G protein couplingShane C Wright, Charlotte Avet, Supriya A Gaitonde, et al.Science Signaling|November 25, 2025
SOS1 inhibition suppresses the emergence of osimertinib resistance to generate a durable response in EGFR-mutant lung cancerBrianna R Daley, Patricia L Theard, Jacob M Hughes, et al.Pageof 321