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Science Signaling|August 25, 2026
BRAF recruitment to spinal sensory synapses promotes neuropathic pain by potentiating transsynaptic NMDA receptor activityDaozhong Jin, Hong Chen, Yuying Huang, et al.Science Signaling|August 18, 2026
Distinct properties of glutamate-dopamine, nonglutamate-dopamine, and glutamate-only ventral tegmental area neuronsEmily D Prévost, Lucy A Ward, Daniel Alas, et al.Science Signaling|September 29, 2026
Light-induced remodeling of the Drosophila phosphoproteome regulates visual adaptation through the Trp channelLucas D Kramer, Tal Brandwine-Shemmer, Leah R Pierce, et al.Science Signaling|June 3, 2025
Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent painHannah Gerninghaus, Jörg Isensee, Lea Kennel, et al.Science Signaling|October 13, 2026
Clusters of GSDMD and GSDME mediate neutrophil pyroptosis in cryopyrin-associated periodic syndromeZheHao Tan, Sahand Salari Namin, Janset Onyuru, et al.Science Signaling|September 15, 2026
The RAMP3 proximity interactor MYO6 determines spatiotemporal signaling of the GPCR CLR in lymphatic endothelial cellsD Stephen Serafin, Monserrat Avila-Zozaya, Poonam Kumari, et al.Science Signaling|October 6, 2026
Metabolic reprogramming of pathogenic CD4+ T helper cells attenuates inflammatory bowel disease in miceShravan K Mishra, Leena M Abdelrahman, Hyun Se Kim Lee, et al.Science Signaling|October 27, 2026
Disruption of the N-terminal domain in a STAT3 hyper-IgE syndrome variant causes disease by sequestering STAT3 in the cytoplasmJoseph Mackie, Dan Suan, David B Langley, et al.Science Signaling|October 27, 2026
Neuronal tRNA modifications in Aplysia californica are repatterned during behavioral habituationHan Xin Huang, Gabriella M Floro, Emmanuel Asare, et al.Pageof 321