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Science Signaling|December 3, 2024
Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's diseaseMahta Barekatain, Linda C Johansson, Jordy H Lam, et al.Science Signaling|March 4, 2025
The acetyltransferase GCN5 contributes to neuroinflammation in mice by acetylating and activating the NF-κB subunit p65 in microgliaDuk-Yeon Cho, Jun-Hyuk Han, In-Su Kim, et al.Science Signaling|August 27, 2024
Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytesJamil Mahmud, Brittany W Geiler, Juthi Biswas, et al.Science Signaling|August 20, 2024
The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammationHyunjoon Kim, Yeonglim Kang, Semi Kim, et al.Science Signaling|November 5, 2024
Extracellular proximal interaction profiling by cell surface-targeted TurboID reveals LDLR as a partner of liganded EGFRRasha Al Mismar, Payman Samavarchi-Tehrani, Brendon Seale, et al.Science Signaling|October 29, 2024
The de novo purine synthesis enzyme Adssl1 promotes cardiomyocyte proliferation and cardiac regenerationZhigang Li, Xiaxi Dong, Lingfang Zhuang, et al.Science Signaling|August 6, 2024
Poly-GR repeats associated with ALS/FTD gene C9ORF72 impair translation elongation and induce a ribotoxic stress response in neuronsDaoyuan Dong, Zhe Zhang, Yini Li, et al.Science Signaling|July 2, 2024
Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signalingYusman Manchanda, Liliane ElEid, Affiong I Oqua, et al.Pageof 321