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Science Signaling|July 29, 2025
Proteomic analyses identify targets, pathways, and cellular consequences of oncogenic KRAS signalingNicole Kabella, Florian P Bayer, Konstantinos Stamatiou, et al.Science Signaling|September 19, 2013
The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosisSivareddy Kotla, Nikhlesh K Singh, Mark R Heckle, et al.Science Signaling|July 25, 2014
REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signalingMichael D Dennis, Catherine S Coleman, Arthur Berg, et al.Science Signaling|July 31, 2014
MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancerUmadevi Thirumurthi, Jia Shen, Weiya Xia, et al.Science Signaling|August 7, 2014
Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migrationJuliane Mooz, Tripat Kaur Oberoi-Khanuja, Gregory S Harms, et al.Science Signaling|July 17, 2014
The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cellsVivian Gama, Vijay Swahari, Johanna Schafer, et al.Science Signaling|August 14, 2014
Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastomaYael Kusne, Eugenio A Carrera-Silva, Anthony S Perry, et al.Science Signaling|August 14, 2014
The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in miceSimona Infantino, Sarah A Jones, Jennifer A Walker, et al.Science Signaling|May 16, 2013
Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3Bo Zhong, Xikui Liu, Xiaohu Wang, et al.Pageof 321