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Science Signaling|June 25, 2015
Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partnersMinos-Timotheos Matsoukas, Álvaro Aranguren-Ibáñez, Teresa Lozano, et al.Science Signaling|June 4, 2020
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cellsCesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, et al.Science Signaling|May 28, 2020
The tale of a tail: The secret behind IGF-1R's oncogenic powerCaitrin Crudden, Leonard GirnitaScience Signaling|August 25, 2021
Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo functionAlexander I Salter, Anusha Rajan, Jacob J Kennedy, et al.Science Signaling|August 9, 2022
Heterogeneity in RAS mutations: One size does not fit allNancy E Sealover, Robert L KortumScience Signaling|August 16, 2022
IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cellsLily L Remsing Rix, Natalia J Sumi, Qianqian Hu, et al.Science Signaling|May 21, 2015
The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathwayHanna Sjölin Goodfellow, Maria P Frushicheva, Qinqin Ji, et al.Science Signaling|June 18, 2015
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylationShanmugam Panneer Selvam, Ryan M De Palma, Joshua J Oaks, et al.Science Signaling|June 18, 2015
Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulationQiong Xue, Yao Lu, Markus R Eisele, et al.Science Signaling|June 18, 2015
Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesiclesMateja Manček-Keber, Mojca Frank-Bertoncelj, Iva Hafner-Bratkovič, et al.Pageof 321