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Science Translational Medicine|January 7, 2026
Lenacapavir treatment-emergent HIV-1 capsid resistance mutations are frequently associated with replication defectsNina Pennetzdorfer, Vidula Naik, Sally Demirdjian, et al.Science Translational Medicine|January 14, 2026
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline gliomaHolly Holliday, Aaminah Khan, Anahid Ehteda, et al.Science Translational Medicine|January 7, 2026
Clinical testing of drug treatment shortening in patients with TB using PET/CT imaging of lung lesionsStephanus T Malherbe, Ray Y Chen, Xiang Yu, et al.Science Translational Medicine|November 12, 2025
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosusShady Younis, Salvinaz I Moutusy, Sajede Rasouli, et al.Science Translational Medicine|November 12, 2025
Incorporation of 5-methylcytidine alleviates RIG-I-mediated innate immune responses to a self-amplifying RNA vaccineWataru Akahata, Mai Komori, Amber L Morey, et al.Science Translational Medicine|November 19, 2025
Target antigen-displaying extracellular vesicles boost CAR T cell efficacy in cell and mouse models of neuroblastomaAnna Maria Giudice, Stephanie Matlaga, Sydney L Roth, et al.Science Translational Medicine|November 12, 2025
EBV and the making of lupusGuy Gorochov, Alexis MathianScience Translational Medicine|November 12, 2025
Blood-brain barrier opening with neuronavigation-guided focused ultrasound in pediatric patients with diffuse midline gliomaCheng-Chia Wu, Luca Szalontay, Antonios N Pouliopoulos, et al.Science Translational Medicine|January 7, 2026
When HIV pays the price: Fitness costs behind lenacapavir resistanceManish C Choudhary, Jonathan Z LiScience Translational Medicine|December 24, 2025
FcγR-targeted tuftsin clusters rejuvenate macrophages in preclinical sepsis-associated secondary infectionGuangchao Qing, Yuxuan Zhang, Yongchao Wang, et al.Pageof 482