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Science Translational Medicine|August 26, 2026
A 3D human retina model reveals a non-cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorderJimin Han, Nathaniel Foley, Sonal Dalvi, et al.Science Translational Medicine|August 26, 2026
Baseline interferon signaling in monocytes and antibody-mediated innate activation are associated with reactogenicity to mRNA vaccinesNatacha Madelon, Gustavo A Ruiz Buendía, Paula Torres Rodriguez, et al.Science Translational Medicine|August 26, 2026
Urogenital immune signatures are associated with birth outcomes after maternal urinary tract infectionSamantha Ottinger, Addison B Larson, Vicki Mercado-Evans, et al.Science Translational Medicine|August 26, 2026
Aberrant alternative splicing memorized in adipose tissue macrophages impedes efferocytosis during postobesity weight lossTakuro Miyazaki, Akira Shiraishi, Yuki Sugiura, et al.Science Translational Medicine|August 19, 2026
MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse modelM Catarina Silva, Hannah Lindmeier, Paolo Pigini, et al.Science Translational Medicine|May 28, 2025
Systemic delivery of cadherin 17-specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastasesBeatrice Greco, Rita El Khoury, Chiara Balestrieri, et al.Science Translational Medicine|August 26, 2026
LTBP4 deficiency induces MRC1+/CD44+ macrophages to drive cancer progression in preclinical colorectal cancer modelsSongtao Ji, Shuya Du, Ge Miao, et al.Science Translational Medicine|September 2, 2026
Tissue origins and immune correlates of viral rebound in SIV-infected rhesus macaques after ART discontinuationIrena V King, Malika Aid, Emek Kose, et al.Science Translational Medicine|September 2, 2026
Multifunctional antibody responses from a primate Shigella outbreak inform vaccine designRobert M Gallant, Paul Savarino, Sophia Pulido, et al.Science Translational Medicine|September 2, 2026
MicroRNA-224 orchestrates BMP and TGFβ signaling and is a therapeutic target in preclinical pulmonary arterial hypertensionOlympia Bikou, Aymen Halouani, Yifei Sun, et al.Pageof 483