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Science Translational Medicine|September 24, 2020
A stepped-wedge randomized trial and qualitative survey of HIV pre-exposure prophylaxis uptake in the Eswatini populationPascal Geldsetzer, Kate Bärnighausen, Anita Hettema, et al.Science Translational Medicine|September 24, 2020
Analysis of spatial osteochondral heterogeneity in advanced knee osteoarthritis exposes influence of joint alignmentSophie Haberkamp, Tamás Oláh, Patrick Orth, et al.Science Translational Medicine|October 1, 2020
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetaseSumiti Vinayak, Rajiv S Jumani, Peter Miller, et al.Science Translational Medicine|December 17, 2020
Plasma exosomal miR-375-3p regulates mitochondria-dependent keratinocyte apoptosis by targeting XIAP in severe drug-induced skin reactionsChen Zhang, ZhenLai Zhu, JiXin Gao, et al.Science Translational Medicine|December 17, 2020
Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different speciesUfuk Karakus, Dilara Sahin, Peer R E Mittl, et al.Science Translational Medicine|November 26, 2020
PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humansRaziel Rojas-Rodriguez, Rachel Ziegler, Tiffany DeSouza, et al.Science Translational Medicine|November 26, 2020
Antitumor activity without on-target off-tumor toxicity of GD2-chimeric antigen receptor T cells in patients with neuroblastomaKarin Straathof, Barry Flutter, Rebecca Wallace, et al.Science Translational Medicine|November 26, 2020
Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humansSabrina Simoes, Jessica L Neufeld, Gallen Triana-Baltzer, et al.Science Translational Medicine|November 26, 2020
Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapyMeixi Hao, Siyuan Hou, Weishuo Li, et al.Science Translational Medicine|November 26, 2020
Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantationLam T Khuat, Catherine T Le, Chien-Chun Steven Pai, et al.Pageof 484