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Science Translational Medicine|July 16, 2025
Targeting SIRT2 induces MLH1 deficiency and boosts antitumor immunity in preclinical colorectal cancer modelsQianling Gao, Lanlan Yang, Shubiao Ye, et al.Science Translational Medicine|July 16, 2025
Donor-recipient mismatch at the SIRPA locus adversely affects kidney allograft outcomesDaqiang Zhao, Hehua Dai, Camila Macedo, et al.Science Translational Medicine|July 16, 2025
Complement is activated in patients with acute chest syndrome caused by sickle cell disease and represents a therapeutic targetSatheesh Chonat, Jayre A Jones, Seema R Patel, et al.Science Translational Medicine|July 16, 2025
S100A8/A9 perturbation in bone marrow blunts antitumor immunity by promoting protumorigenic myelopoiesis in mouse modelsWen Luo, Xingxing Su, Qiao Zhang, et al.Science Translational Medicine|December 17, 2025
Distinct systemic immune responses in asymptomatic and symptomatic dengue virus infectionWaradon Sungnak, Natnicha Jiravejchakul, Tiraput Poonpanichakul, et al.Science Translational Medicine|December 17, 2025
Coordinate tumor-antigen uptake and dendritic cell activation by chimeric antigen receptorsYahya Mohammadzadeh, Vojislav Gligorovski, Olga Egorova, et al.Science Translational Medicine|December 17, 2025
Single-amino acid variants in target epitopes can confer resistance to antibody-based therapiesRomina Marone, Erblin Asllanaj, Giuseppina Capoferri, et al.Science Translational Medicine|December 10, 2025
Farm exposure in infancy is associated with elevated systemic IgG4, mucosal IgA responses, and lower incidence of food allergyCourtney M Jackson, Elizabeth Ponko, Natalie M Vance, et al.Science Translational Medicine|December 3, 2025
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosisLaura Seldeslachts, Sirima Kraisin, Intan M W Dewi, et al.Science Translational Medicine|December 10, 2025
A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical modelsTao Zhang, Tingyun Lei, Jie Han, et al.Pageof 484