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Science Translational Medicine|December 17, 2025
Single-amino acid variants in target epitopes can confer resistance to antibody-based therapiesRomina Marone, Erblin Asllanaj, Giuseppina Capoferri, et al.
Science Translational Medicine|December 10, 2025
Farm exposure in infancy is associated with elevated systemic IgG4, mucosal IgA responses, and lower incidence of food allergyCourtney M Jackson, Elizabeth Ponko, Natalie M Vance, et al.
Science Translational Medicine|December 3, 2025
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosisLaura Seldeslachts, Sirima Kraisin, Intan M W Dewi, et al.
Science Translational Medicine|December 10, 2025
A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical modelsTao Zhang, Tingyun Lei, Jie Han, et al.
Science Translational Medicine|February 12, 2025
Intestinal epithelium-derived IL-34 reprograms macrophages to mitigate gastrointestinal tract graft-versus-host diseaseAditya Rayasam, Alison Moe, Matthew Kudek, et al.
Science Translational Medicine|February 5, 2025
Selection and prioritization of candidate combination regimens for the treatment of tuberculosisNatasha Strydom, Rob C van Wijk, Qianwen Wang, et al.
Science Translational Medicine|January 29, 2025
AGER-dependent macropinocytosis drives resistance to KRAS-G12D-targeted therapy in advanced pancreatic cancerChangfeng Li, Yuanda Liu, Chang Liu, et al.
Science Translational Medicine|January 29, 2025
Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infectionLeslie Chan, Kassandra Pinedo, Mikayla A Stabile, et al.
Science Translational Medicine|February 19, 2025
Gluconolactone restores immune regulation and alleviates skin inflammation in lupus-prone mice and in patients with cutaneous lupusWei Li, Antonios G A Kolios, Wenliang Pan, et al.
Science Translational Medicine|February 19, 2025
Dysfunctional CD11c-CD21- extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancerAyana T Ruffin, Allison N Casey, Sheryl R Kunning, et al.
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