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Science Translational Medicine|November 27, 2024
An mRNA-encoded dominant-negative inhibitor of transcription factor RUNX1 suppresses vitreoretinal disease in experimental modelsMichael O'Hare, William P Miller, Said Arevalo-Alquichire, et al.Science Translational Medicine|May 20, 2026
Treating the immune system to repair the brainMichal Schwartz, Tommaso CroeseScience Translational Medicine|May 20, 2026
Real-time in vivo analysis of murine β cells reveals autophagic flux defects before onset of autoimmune diabetesOlha Melnyk, Charanya Muralidharan, Bryce E Duffett, et al.Science Translational Medicine|May 20, 2026
A mitochondrial ROS-dependent antiviral response promotes β cell resilience and is diminished in donors with type 1 diabetesLeslie E Wagner, Olha Melnyk, Alissa N Muncy, et al.Science Translational Medicine|June 10, 2026
The pyrrolidinamide antimalarial drug MMV367 rapidly clears blood-stage Plasmodium falciparum in healthy adults with experimental malariaBridget E Barber, Robin Denhardt-Eriksson, Etienne A Guirou, et al.Science Translational Medicine|June 10, 2026
SARS-CoV-2 variant booster vaccination and infection alter the breadth of the memory B cell repertoireRory Malek, Flavio Matassoli, Kyle Gordon, et al.Science Translational Medicine|May 27, 2026
Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situJu Zhang, Li Chen, Xingyu Zhu, et al.Science Translational Medicine|May 27, 2026
Efficacy and safety of durcabtagene autoleucel in a phase 1 trial for patients with relapsed/refractory multiple myelomaAdam S Sperling, Benjamin A Derman, Sarah Nikiforow, et al.Science Translational Medicine|May 27, 2026
The PET tracer [11C]MODAG-005 targets alpha-synuclein aggregates in the brainRan Sing Saw, Sabrina Haas, Felix Schmidt, et al.Science Translational Medicine|May 27, 2026
Genomic instability drives POSTN+ myofibroblasts via STING-WNT axis to promote immunosuppression and PARPi resistance in ovarian cancerDan Liu, Kangjia Tao, Chujun Cai, et al.Pageof 489