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Science Translational Medicine|September 23, 2026
The guanine nucleotide exchange factor Rin-like is a repressor for renal uric acid excretion in human and mouseChangshun Han, Chengyong He, Weiping Hu, et al.Science Translational Medicine|October 7, 2026
Immunoregulatory artificial lymph nodes restore antigen-specific tolerance in advanced multiple sclerosisJingsen Ji, Xinhuan Wang, Lu Liu, et al.Science Translational Medicine|September 30, 2026
A single-dose topical therapy cures scabies in a human-relevant porcine modelDeepani Darshika Fernando, Sara Taylor, Gangi Rameshika Samarawickrama, et al.Science Translational Medicine|October 14, 2026
Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer's diseaseBorislav Dejanovic, Matthew D Figley, Elizabeth Weisman, et al.Science Translational Medicine|October 14, 2026
Metabolomic aging and mortality clocks based on ensemble learning identify systemic aging risk across the human life span in 18,476 individualsLinlin Cao, Yifan Chen, Wei Zhang, et al.Science Translational Medicine|October 14, 2026
From code to cure: Harnessing AI for antibiotic discovery and designAarti Krishnan, Hanqun Cao, James J Collins, et al.Science Translational Medicine|October 22, 2026
Targeting ZIP12-mediated Zn2+ signaling as a treatment for pulmonary hypertensionLan Zhao, Stephanie Hopley, Chien-Nien Chen, et al.Science Translational Medicine|October 22, 2026
The kinase inhibitor dabrafenib halts progression of cerebral cavernous malformations in a BRAF-independent mannerMaximiliano Arce, Hua Huang, Charlotte Rorsman, et al.Science Translational Medicine|October 28, 2026
Keratinocyte-derived CHI3L2 reprograms phospholipid metabolism to promote skin inflammation in psoriasisFei Li, Wentao Zhang, Wenxian Ma, et al.Science Translational Medicine|October 28, 2026
Acute kidney injury as a systemic diseaseHannah M M Preston, Richard Shemilt, Fiona A Chapman, et al.Pageof 489