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Signal Transduction and Targeted Therapy|July 13, 2025
High mtDNA content identifies oxidative phosphorylation-driven acute myeloid leukemias and represents a therapeutic vulnerabilityDiego A Pereira-Martins, Isabel Weinhäuser, Emmanuel Griessinger, et al.
Signal Transduction and Targeted Therapy|July 20, 2025
Differential expression pattern of CC chemokine receptor 7 guides precision treatment of hepatocellular carcinomaJie Qin, Qianyi Gong, Cheng Zhou, et al.
Signal Transduction and Targeted Therapy|July 3, 2025
CAR-T cell therapy for cancer: current challenges and future directionsInés Zugasti, Lady Espinosa-Aroca, Klaudyna Fidyt, et al.
Signal Transduction and Targeted Therapy|July 9, 2025
Targeting CD155 in lung adenocarcinoma: A5 nanobody-based therapeutics for precision treatment and enhanced drug deliveryKyunghee Noh, Soyeon Yi, Hyeran Kim, et al.
Signal Transduction and Targeted Therapy|July 27, 2025
Efficacy and safety of IBI351 (fulzerasib) monotherapy in KRASG12C inhibitor-naïve Chinese patients with KRASG12C-mutated metastatic colorectal cancer: a pooled analysis from phase I part of two studiesYing Yuan, Yanhong Deng, Yongdong Jin, et al.
Signal Transduction and Targeted Therapy|July 27, 2025
Genetic subtype-guided immunochemotherapy in relapsed and refractory diffuse large B cell lymphoma: a phase 2 investigator-initiated nonrandomized clinical trial (GUIDANCE-06)Yi-Ge Shen, Qing Shi, Wei Tang, et al.
Signal Transduction and Targeted Therapy|July 22, 2025
Molecular mechanisms of unique therapeutic potential of CUDC-907 for MEF2D fusion-driven BCP-ALLQing Xue, Ming Zhang, Yixiao Mo, et al.
Signal Transduction and Targeted Therapy|July 23, 2025
Pseudohypoxic stabilization of HIF1α via cyclophilin D suppression promotes melanoma metastasisHye-Kyung Park, Sung Hu, So Yeon Kim, et al.
Signal Transduction and Targeted Therapy|June 26, 2025
D-lactate and glycerol as potential biomarkers of sorafenib activity in hepatocellular carcinomaSilvia Pedretti, Francesca Palermo, Miriana Braghin, et al.
Signal Transduction and Targeted Therapy|June 30, 2025
Signaling pathways and targeted therapy for pulmonary hypertensionJoseph Adu-Amankwaah, Yue Shi, Hequn Song, et al.
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