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Signal Transduction and Targeted Therapy|March 13, 2026
Cyclic guanosine monophosphate-protein kinase G signaling attenuates aortic valve calcification through ULK1-mediated autophagyYan Wang, Fei Xu, Chengxiang Song, et al.
Signal Transduction and Targeted Therapy|March 17, 2026
Nanoparticles-based phototherapy systems: molecular mechanisms and clinical applicationsDeepak S Chauhan, Rajendra Prasad, Mukesh Dhanka, et al.
Signal Transduction and Targeted Therapy|March 12, 2026
Ubiquitin-mediated stabilization of KDM5B drives chemoresistance via repression of dual-specificity phosphatase 4 in ovarian cancerJung Yoo, Go Woon Kim, Yu Hyun Jeon, et al.
Signal Transduction and Targeted Therapy|March 10, 2026
Synergistic immunotherapeutic effects of irreversible electroporation and CAR-NK cell therapy against hepatocellular carcinomaJoo Dong Park, Ha Eun Shin, Hye Jung Jang, et al.
Signal Transduction and Targeted Therapy|March 10, 2026
Cytotoxic CD4+ T cells: origin, biological functions, diseases and therapeutic targetsLongyong Lai, Shuan Ran, Yuan Li, et al.
Signal Transduction and Targeted Therapy|June 10, 2026
Targeting NFATc1-regulated MTHFD2 one-carbon metabolism to suppress sustained T-cell-mediated inflammation in rheumatoid arthritisTheodora Manolakou, Jianyu Shen, Sanjaykumar Boddul, et al.
Signal Transduction and Targeted Therapy|June 10, 2026
Advancing high-altitude medicine: a model for the futureWenjin Sun, Xuan Zhang, Ling Chen, et al.
Signal Transduction and Targeted Therapy|April 26, 2026
Therapeutic targeting of BCL-2 during CART cell production augments potency through non-apoptotic adaptive changesNada S Aboelella, Ryan Park, Erting Tang, et al.
Signal Transduction and Targeted Therapy|March 26, 2026
Oligodendrocyte precursor cells-microglia crosstalk via BMP4 drives microglial neuroprotective response and mitigates Alzheimer's diseaseSoonbong Baek, Jaemyung Jang, Seungeun Yeo, et al.
Signal Transduction and Targeted Therapy|April 27, 2026
Targeting GPR34 in damage-associated macrophages enhances anti-tumor immunity and the efficacy of Surufatinib in pancreatic cancerXiaofan Guo, Yuxiao Liu, Tianchen Li, et al.
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