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Signal Transduction and Targeted Therapy|August 6, 2026
RNA methyltransferase 3 drives pancreatic acinar cell carcinoma growth and is a therapeutic targetShotaro Tatekawa, Tomoaki Hara, Sikun Meng, et al.
Signal Transduction and Targeted Therapy|August 12, 2026
Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III studyJia Yu, Anwen Xiong, Qiming Wang, et al.
Signal Transduction and Targeted Therapy|August 13, 2026
Oral nonpeptide GLP-1 receptor agonist VCT220 for obesity treatment: a randomized, double-blind, phase II trialLinong Ji, Leili Gao, Ben Li, et al.
Signal Transduction and Targeted Therapy|August 11, 2026
Temperature-sensitive liquid embolic agent transarterial chemoembolization versus drug-eluting bead transarterial chemoembolization for BCLC Stage B/C hepatocellular carcinoma: a multicenter real-world study and spatial transcriptomics profiling (CHANCE 2515)Qingyun Xie, Ying Yang, Sinan Xie, et al.
Signal Transduction and Targeted Therapy|August 18, 2026
Role of epithelial-mesenchymal transition (EMT) in malignancies: current status and future prospectsVafa Meftahpour, Tikam Chand Dakal, Jarek Maciaczyk, et al.
Signal Transduction and Targeted Therapy|August 10, 2026
C-MET tyrosine kinase receptor: mechanisms, clinical applications and future perspectives in cancer therapyChenjing Zhu, Yue Li, Hanzi Xu, et al.
Signal Transduction and Targeted Therapy|August 19, 2026
Biallelic loss of RB1 in hepatocellular carcinoma as synthetic lethal target for artificial intelligence-guided therapyJihyun An, Wonkyung Kim, Xiumei Zhang, et al.
Signal Transduction and Targeted Therapy|August 19, 2026
Single-cell multiomics reveals exosome-mediated reprogramming and clonotypic remodeling of T cells in triple-negative breast cancerSanam Rezaei Benam, Samaneh Maleknia, Kent Williams, et al.
Signal Transduction and Targeted Therapy|August 23, 2026
The making of cells and organs in xenogeneic animal bioreactorYunhan Tang, Ye Feng, Zhu Chen, et al.
Signal Transduction and Targeted Therapy|August 31, 2026
First-line anlotinib versus bevacizumab plus CapeOX in RAS/BRAF wild-type unresectable metastatic colorectal cancer (ANCHOR): a multicenter, prospective, randomized, phase 3 trialYue Liu, Yanqiao Zhang, Rongbo Lin, et al.
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