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Signal Transduction and Targeted Therapy|May 11, 2026
The evolving global landscape of first-in-class oncology drug innovationXiangyun Mao, Zhaoqing Wang, Shu Kong, et al.
Signal Transduction and Targeted Therapy|May 11, 2026
A specific stem cell program and CD112 immunological axis dysfunctions underpinning monosomy 7-associated myeloid neoplasmsAnair Graciela Lema Fernandez, Carlotta Nardelli, Martina Quintini, et al.
Signal Transduction and Targeted Therapy|April 30, 2026
BMAL1 regulates circadian rhythms via phase separation-mediated transcriptional hub formationWenzhen Gao, Li Zhu, Yali Wei, et al.
Signal Transduction and Targeted Therapy|April 9, 2026
Cortisol-resistant CAR-NK cells overcome steroid-induced immunosuppression in lung cancerSoura Chakraborty, Jhuma Pramanik, Gustavo Alviter-Raymundo, et al.
Signal Transduction and Targeted Therapy|April 15, 2026
HDAC inhibitor tucidinostat and metronomic capecitabine plus endocrine therapy for patients with HR-positive HER2-negative advanced breast cancer after CDK4/6 inhibitors treatment: clinical findings and exploratory circulating tumor cell and ctDNA biomarker analyses of a multicenter, phase 2 study (SYSUCC-020 trial)Huai-Liang Wu, Wen Xia, Zhengyang Xu, et al.
Signal Transduction and Targeted Therapy|April 15, 2026
Esophageal cancer: from pathogenesis to precision therapiesShaosen Zhang, Yanrong Shen, Lingxuan Zhu, et al.
Signal Transduction and Targeted Therapy|April 22, 2026
Sexual dimorphism of COVID-19 inspires drug repositioning and host-targeting immunotherapy for viral pneumoniaLunzhi Yuan, Haiqing Xiao, Xuan Liu, et al.
Signal Transduction and Targeted Therapy|May 6, 2026
ADAMTS4 elicits myeloid-derived immune cell recruitment and liver fibrogenesis in metabolic dysfunction-associated steatotic liver diseaseJeongwoo Park, Taeeung Kim, Wan Seob Shim, et al.
Signal Transduction and Targeted Therapy|May 4, 2026
ENO2 drives tumor cell-induced M2 macrophage polarization to promote colorectal cancer liver metastasisJunwei Tang, Zhihao Chen, Dongsheng Zhang, et al.
Signal Transduction and Targeted Therapy|April 7, 2026
Prostaglandin E2-driven dedifferentiation of Schwann cells leads to perineural invasion in pancreatic ductal adenocarcinomaLing Wang, Qicai Liu, Zhibo Zhang, et al.
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