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Signal Transduction and Targeted Therapy|August 13, 2025
Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategiesGangling Xu, Jing Jin, Zhihao Fu, et al.
Signal Transduction and Targeted Therapy|August 13, 2025
Single-cell RNA sequencing identifies the prolactin receptor as a therapeutic target in adenomyosisRunze Wang, Shuai Xu, Qionghua Cui, et al.
Signal Transduction and Targeted Therapy|August 4, 2025
Cancer stem cells: landscape, challenges and emerging therapeutic innovationsHaksoo Lee, Byeongsoo Kim, Junhyeong Park, et al.
Signal Transduction and Targeted Therapy|November 13, 2025
Oligomeric cystatin C supports the immunosuppressive activity of myeloid cells through interaction with inhibitory receptorsChengcheng Zhang, Yubo He, Xiaoye Liu, et al.
Signal Transduction and Targeted Therapy|November 10, 2025
Ablation plus immunotherapy versus immunotherapy alone in patients of advanced NSCLC who develop oligo-residual disease after anti-PD-1/L1 therapy (BOOSTER): a randomized phase 2 trialShuo Yang, Xinyu Liu, Jia Yu, et al.
Signal Transduction and Targeted Therapy|October 21, 2025
Proliferative diabetic retinopathy subtypes defined by immune defense and endothelial mitochondrial dysfunctionMaximilian A McCann, Basma Baccouche, Yueru Li, et al.
Signal Transduction and Targeted Therapy|October 20, 2025
Condensate nanovaccine adjuvants augment CD8+ T-Cell-dependent antitumor immunity through mtDNA leakage-triggered cGAS-STING axis activationYu Tang, Zhiyuan Luo, Zhanni Ma, et al.
Signal Transduction and Targeted Therapy|July 21, 2025
Exploratory phase II trial of an anti-PD-1 antibody camrelizumab combined with a VEGFR-2 inhibitor apatinib and chemotherapy as a neoadjuvant therapy for triple-negative breast cancer (NeoPanDa03): efficacy, safety and biomarker analysisXiaoxiao Liu, Chunying Zhuang, Lei Liu, et al.
Signal Transduction and Targeted Therapy|July 18, 2025
Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progressionBin Cheng, Pai Peng, Shi Chen, et al.
Signal Transduction and Targeted Therapy|July 17, 2025
Targeting epigenetic regulators as a promising avenue to overcome cancer therapy resistanceJiawei Song, Ping Yang, Canting Chen, et al.
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