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Signal Transduction and Targeted Therapy|January 14, 2026
The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progressionChoong-Jae Lee, Hyeon-Ji Yun, Tae-Young Jang, et al.
Signal Transduction and Targeted Therapy|January 22, 2026
Altitude hypoxia and hypoxemia: pathogenesis and managementChunmei Cai, Guohua Ni, Lei Chen, et al.
Signal Transduction and Targeted Therapy|January 25, 2026
Targeting metabolic-epigenetic-immune axis in cancer: molecular mechanisms and therapeutic implicationsXing Wang, Xiyuan Luo, Ruiling Xiao, et al.
Signal Transduction and Targeted Therapy|January 19, 2026
Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinomaUgo Chianese, Chiara Papulino, Gerardo Saggese, et al.
Signal Transduction and Targeted Therapy|January 12, 2026
MAPK14 converges on key transcriptional machinery to promote vascular smooth muscle cell degeneration in abdominal aortic aneurysmXiaoliang Wu, Chunhui Wang, Nestor Ishimwe, et al.
Signal Transduction and Targeted Therapy|February 17, 2026
Ring finger protein 213 regulates B-cell receptor signaling, metabolism, and development in B lymphocytesZiyin Zhang, Nanshu Xiang, Qian Liu, et al.
Signal Transduction and Targeted Therapy|February 2, 2026
Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2Ke Wang, Peng Lin, Ruo Chen, et al.
Signal Transduction and Targeted Therapy|February 3, 2026
Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STINGJieqiong Wang, Alexander Mrozek, Kewen Hu, et al.
Signal Transduction and Targeted Therapy|November 23, 2025
Social memory maintenance relies on social interaction-induced proteolytic products of neuroligin 1An Liu, Xingcan Li, Mei Zhuang, et al.
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