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The AAPS Journal|November 19, 2020
A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer TherapyMeina Liang, Bing Wang, Amy Schneider, et al.The AAPS Journal|January 18, 2023
Model-Informed Approach Supporting Approval of Nexviazyme (Avalglucosidase Alfa-ngpt) in Pediatric Patients with Late-Onset Pompe DiseaseRuo-Jing Li, Lian Ma, Katarzyna Drozda, et al.The AAPS Journal|June 28, 2021
Cannabinoid Interactions with Cytochrome P450 Drug Metabolism: a Full-Spectrum CharacterizationPeter T Doohan, Lachlan D Oldfield, Jonathon C Arnold, et al.The AAPS Journal|June 30, 2021
FDA's Poly (Lactic-Co-Glycolic Acid) Research Program and Regulatory OutcomesYan Wang, Bin Qin, Grace Xia, et al.The AAPS Journal|January 6, 2021
Application of Model Informed Precision Dosing to Address the Impact of Pregnancy Stage and CYP2D6 Phenotype on Foetal Morphine ExposureSarah Badaoui, Ashley M Hopkins, A David Rodrigues, et al.The AAPS Journal|January 13, 2021
Human Fetal Liver Metabolism of Oxycodone Is Mediated by CYP3A7Sara Shum, Nina IsoherranenThe AAPS Journal|June 25, 2021
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and FetusKe Xu Szeto, Maxime Le Merdy, Benjamin Dupont, et al.The AAPS Journal|June 25, 2021
Formoterol PLGA-PEG Nanoparticles Induce Mitochondrial Biogenesis in Renal Proximal TubulesErnest L Vallorz, Karen Blohm-Mangone, Rick G Schnellmann, et al.The AAPS Journal|June 3, 2021
Therapeutic Genome Editing and In Vivo DeliveryAmanda Catalina Ramirez-Phillips, Dexi LiuThe AAPS Journal|June 1, 2022
Opportunities and Challenges for PBPK Model of mAbs in Paediatrics and PregnancyKatherine L Gill, Hannah M JonesPageof 235