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The AAPS Journal|September 12, 2023
Ensemble Machine Learning Approaches Based on Molecular Descriptors and Graph Convolutional Networks for Predicting the Efflux Activities of MDR1 and BCRP TransportersAsahi Adachi, Tomoki Yamashita, Shigehiko Kanaya, et al.
The AAPS Journal|June 20, 2023
Multifaceted Approach for Quantification and Enzymatic Activity of Iduronate-2-Sulfatase to Support Developing Gene Therapy for Hunter SyndromePeter M Franchi, Nadia Kulagina, Anna Ilinskaya, et al.
The AAPS Journal|June 29, 2023
Enhanced Pharmacokinetic Bioanalysis of Antibody-drug Conjugates using Hybrid Immunoaffinity Capture and Microflow LC-MS/MSMoo-Jin Suh, Joshua B Powers, Casey M Daniels, et al.
The AAPS Journal|June 29, 2023
Integration of Biorelevant Pediatric Dissolution Methodology into PBPK Modeling to Predict In Vivo Performance and Bioequivalence of Generic Drugs in Pediatric Populations: a Carbamazepine Case StudyGopal Pawar, Fang Wu, Liang Zhao, et al.
The AAPS Journal|March 10, 2026
PQRI Workshop: Model-Informed Drug Development (MIDD) Approaches in Pediatric Formulation DevelopmentGilbert J Burckart, Susan Abdel-Rahman, Caleb Choi, et al.
The AAPS Journal|March 14, 2026
PBPK Modelling of Antisense Oligonucleotide Therapeutics: Application for Predicting Plasma and Tissue Pharmacokinetics of BepirovirsenFarzaneh Salem, Felix Stader, Amir S Youssef, et al.
The AAPS Journal|March 3, 2026
Simultaneous LC-MS/MS Quantification Method for Cassette-Dosing Pharmacokinetics Study of Monoclonal Antibodies Using Alanine Modifications in Constant RegionTakuya Ichikawa, Naoka Hironiwa, Naoaki Murao, et al.
The AAPS Journal|June 11, 2024
Physiologically Based Biopharmaceutics Modeling for Gefapixant IR Formulation Development and Defining the Bioequivalence Dissolution Safe SpaceMichael Wang, Tycho Heimbach, Wei Zhu, et al.
The AAPS Journal|March 28, 2026
PBPK Modelling of PROTACs: Learnings from ARV-110 as a Case ExampleFarzaneh Salem, Ali Tabatabaeian Nimavardi, Abhishek Srivastava, et al.
The AAPS Journal|March 19, 2026
Industry Practices in Monoclonal Antibody Tissue Biodistribution Assessment: An IQ Consortium Cross-Industry Survey of Current Approaches and Emerging TrendsHuaping Tang, Michael McCoy, Antony Leonard, et al.
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