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Trials|September 24, 2025
Estimands in equivalence trials and non-inferiority trials: a cross-sectional study of EMA scientific advice to drug developersJonathan Bergman, Lorenzo Guizzaro, Juan Jose Abellan, et al.
Trials|September 27, 2025
Coenrollment of critically ill patients in PROSPECT: characteristics and association with treatment efficacy and safetyAlex Thabane, Diane Heels-Ansdell, Nicole Zytaruk, et al.
Trials|August 7, 2025
Effectiveness of an educational asthma management program (CuidAR): the protocol for a cluster-randomized trial in the Brazilian primary healthcare settingAna Paula Tussi Leite, Géssica Luana Antunes, Amanda Paz Santos, et al.
Trials|August 7, 2025
Reducing intraoperative hemorrhage in type II caesarean scar pregnancy: a study protocol comparing high-intensity focused ultrasound (HIFU) pretreatment vs. hysteroscopy-guided suction curettage-an open-label, 1:1 parallel-group, superiority-design investigator-initiated trial (IIT)Changmei Sang, Qiuling Shi, Lei Zhao, et al.
Trials|August 12, 2025
Promoting family functioning through physical activity: a randomized trial to evaluate the "All in the Family" programAlfred S Y Lee, Chris M Blanchard, Mark R Beauchamp, et al.
Trials|August 12, 2025
The COMBAT Project: study protocol for the development of a core outcome set for morbidity following surgery in paediatric brain tumour patientsSandhya Trichinopoly Krishna, Nicola Harman, Conor Mallucci, et al.
Trials|August 12, 2025
Nitric oxide for the prevention of postoperative acute kidney injury in patients undergoing surgery for Stanford type A aortic dissection: study protocol for a randomized controlled trialZheyuan Chen, Xiao Han, Lingru Li, et al.
Trials|July 27, 2025
Bringing optimised COVID-19 vaccine schedules to immunocompromised populations: statistical elements and designMichael Dymock, James H McMahon, David Griffin, et al.
Trials|August 22, 2021
Internet-based stress recovery intervention FOREST for healthcare staff amid COVID-19 pandemic: study protocol for a randomized controlled trialLina Jovarauskaite, Austeja Dumarkaite, Inga Truskauskaite-Kuneviciene, et al.
Trials|August 22, 2021
Evaluation of the effectiveness of an incentive strategy on the questionnaire response rate in parents of premature babies: a randomised controlled Study Within A Trial (SWAT) nested within SIFTEdmund Juszczak, Oliver Hewer, Christopher Partlett, et al.
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