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Trials|December 17, 2025
Barriers to randomized trials of integrated care for adolescent mothers in the Caribbean: lessons from the THRIVE trial and the Project Amai in BarbadosHada Fongha Ieong, Mariah Cobbin, Pilar Tlachi, et al.Trials|December 20, 2025
Impact of a two-phase robotic-assisted and home-based training program on falls and fall risk in older adults: a multicenter randomized controlled trialEunyoung Kwag, Alice De Luca, Giorgia Marchesi, et al.Trials|December 19, 2025
Development of a consensus extension of the estimands framework for cluster randomised trials (CRT-estimands): results from an international Delphi studyBrennan C Kahan, Melanie Bahti, Dongquan Bi, et al.Trials|December 9, 2025
Rationale and design of a randomized controlled trial testing the efficacy of Safe South Africa, an intervention to prevent HIV risk behavior and sexual violence among adolescent boysCaroline Kuo, Joseph Wasswa, Lindsay Orchowski, et al.Trials|December 10, 2025
An efficient single-arm Bayesian adaptive trial algorithm to evaluate de-intensified oncologic treatmentYuan Zhong, Zeynep Baskurt, Mahmood Aminilari, et al.Trials|December 11, 2025
Cross-sectoral use of Patient-Reported Outcomes (C-PRO)-the effect on the cost per improvement in quality of life for patients with chronic degenerative shoulder conditions-a protocol for a randomised controlled trialAnne Marie Nyholm, Bente Appel Esbensen, Caroline Louise Westergaard, et al.Trials|December 11, 2025
Automated screening for clinically ascertained loss of cerebral functions in patients with severe brain injury-study protocol for a cluster-randomized interventional trialDaniela Schoene, Martin Roessler, Konrad Pleul, et al.Trials|December 5, 2025
Whole-body electrical stimulation in patients undergoing lung transplantation in Southern Brazil: study protocol of a single-center randomized controlled trialAndrieli Barbieri Garlet, Rodrigo Della Méa Plentz, Natiele Camponogara Righi, et al.Trials|December 6, 2025
Metformin for the treatment of unruptured vertebrobasilar dissecting aneurysm (METTLE): study protocol for a double-blinded randomised controlled trialLinggen Dong, Ziming Xu, Yan Li, et al.Trials|December 5, 2025
Dupilumab step-down strategy to maintain remission in adult and adolescent patients with atopic dermatitis: study protocol for a non-inferiority randomized trial (MADULO)A Foureau, E Faurel-Paul, J B Hardouin, et al.Pageof 1,086