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Trials|February 19, 2026
Azithromycin mass drug administration to reduce child mortality in Niger (AVENIR II): a master protocol for a cluster-randomized adaptive platform trial to evaluate community-based health interventionsAhmed M Arzika, Abdou Amza, Sani Ousmane, et al.Trials|March 2, 2026
Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trialTina Čeh, Jernej Završnik, Nejc ŠarabonTrials|March 4, 2026
TwySHE-an mHealth peer-navigator intervention to increase PrEP and contraceptive use among female university students in Zambia: study protocol of a hybrid effectiveness-implementation randomized controlled trialK Hampanda, A Amstutz, L Nayame, et al.Trials|February 26, 2026
Supporting Evidence-based Responses to Emotional Needs in Emphysema (SERENE): protocol for a randomized, open-label mechanistic trial comparing Coping Skills Training and disease-specific education for depressive symptoms conducted in United States health systemsJoanna L Hart, Daniel Carter, Chloe Hinton, et al.Trials|February 24, 2026
Accountability for care through undoing racism and equity for moms: a study protocol for a cluster randomized trial of data accountability and community-based doula interventions in prenatal practicesRachel Peragallo Urrutia, Angela Tatum Malloy, Cindy McMillan, et al.Trials|February 20, 2026
High-protein enteral nutrition in intensive care unit patients undergoing advanced early mobilization: protocol for a randomized controlled trialGinga Suzuki, Yuji Iwanami, Masayoshi Nakazawa, et al.Trials|February 26, 2026
Presepsin to safely reduce antibiotics in preterm infants (PRESAFE): study protocol for a randomized controlled trial with a concurrent observational studyCharlotte M Nusman, H Rob Taal, Daniel C Vijlbrief, et al.Trials|February 27, 2026
Does ventilator circuit disconnection during lateral positioning reduces the rate of double-lumen endotracheal tube displacement in thoracic surgery? a study protocol for a randomized controlled trialShijiao Lv, Meng Lv, Wenya Du, et al.Trials|February 20, 2026
Factors affecting power in stepped wedge trials when the treatment effect varies with timeAvi Kenny, Emily C Voldal, Fan Xia, et al.Trials|February 20, 2026
Pulsed electromagnetic field therapy versus sham therapy as an adjunct to conventional physiotherapy on pain, functional disability, and quality of life in patients undergoing total hip arthroplasty: a randomized placebo controlled trial protocolAachal Gharjare, Mitushi DeshmukhPageof 1,086