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Trials|May 15, 2025
Efficacy and safety of levothyroxine monotherapy in lowering the risk of cardiovascular disease in older adults with subclinical hypothyroidism: research protocols of a multicenter, open-label, randomized controlled trialChong Xu, Hui Zhou, Xiaofan Lu, et al.
Trials|June 17, 2025
Analgesic effect of premixed nitrous oxide in postoperative rehabilitation for ankle fractures: study protocol for a randomized controlled trialXueling Qiu, Lin Chen, Xiaochen Jiang, et al.
Trials|February 17, 2026
Evaluation of a combined tuberculosis case-finding, treatment and prevention strategy in Thailand: protocol for a pragmatic phase IV stepped-wedge cluster-randomised trial, the CaPThai studyTamara Tovar Sanchez, Jintana Ngamvithayapong-Yanai, Daniel Grint, et al.
Trials|February 17, 2026
Self-Help Plus for refugee mothers in Rhino Refugee Settlement, Uganda (SEED): study protocol for a cluster-randomized controlled trial assessing intergenerational effects on preschool-aged childrenPhaidon T B Vassiliou, Herbert E Ainamani, Stefan Döring, et al.
Trials|February 12, 2026
Protocol for a randomized controlled trial comparing saturated and unsaturated fat sources of a ketogenic diet (KETO-IM) investigating cardiovascular, inflammatory and immune function outcomes in adults living with overweight and prediabetes or type 2 diabetes in Edmonton, CanadaJodie L Harbarenko, Trina Gartke, Paulina Blanco Cervantes, et al.
Trials|February 15, 2026
An integrated behavioral treatment for improving nocturia and insomnia symptoms in older adults (MINT): study protocol for a multi-site randomized clinical trialConstance H Fung, Courtney J Bolstad, Alison Huang, et al.
Trials|February 15, 2026
Development of a Core Outcome Set for research studies with older adults in the Emergency Department-CREAT-ED: A multi-stage study protocolK Mc Loughlin, J Salsberg, R Mc Namara, et al.
Trials|January 29, 2026
Vertigo Coach© application as an adjunct to canalith repositioning techniques to improve dizziness, vertigo severity, and quality of life in patients with posterior canal benign paroxysmal positional vertigo: a randomized controlled trial protocolManjiri Nakhate, Moh'd Irshad Qureshi, Raghumahanti Raghuveer
Trials|January 28, 2026
High-intensity training vs. low-intensity training for patients with anxiety: a randomised controlled trialMartin Bystad, Sveinung Rydland, Christian Bugge, et al.
Trials|January 29, 2026
Strengthening Primary Care for Recognising and Treating Depression (SPiRiT-D): a study protocol for a cluster randomised controlled effectiveness-implementation trial of collaborative care for depressionMehreen Riaz Faisal, Mujeeb Masud Bhatti, Simon Walker, et al.
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