Jukka Hakkola

16PUBLICATIONS
29CO-AUTHORS
Predictive and prognostic markersCell physiologyEnvironmental biogeochemistryMolecular targetsCancer diagnosis
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Publications (16)

|Aug 26, 2026
Pregnane X receptor-mediated liver growth: a controlled clinical trial in healthy volunteers and identification of the role of AKT-MTOR pathway in mouse.

|Jan 14, 2026
Atorvastatin regulates hepatic transcriptome PXR dependently but distinct from pregnenolone 16α-carbonitrile and does not induce PXR-mediated liver steatosis.

Heba Nabil, Mahmoud-Sobhy Elkhwanky, Mohamed Hassanen

|Jan 01, 2026
Unmasking metabolic disruptors: The NEMESIS project's quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies.

Henriikka Hakomäki, Sini Pitkänen, Anna-Liisa Levonen

|Dec 24, 2024
The fungicide propiconazole induces hepatic steatosis and activates PXR in a mouse model of diet-induced obesity.

Brecht Attema, Outi Kummu, Mária Krutáková

|Jan 05, 2024
Metabolic effects of nuclear receptor activation in vivo after 28-day oral exposure to three endocrine-disrupting chemicals.

Brecht Attema, Outi Kummu, Sini Pitkänen

|Aug 29, 2023
Adverse outcome pathway for pregnane X receptor-induced hypercholesterolemia.

Anna Itkonen, Jukka Hakkola, Jaana Rysä

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Frequent Collaborators

5 joint publications

Janne Hukkanen

4 joint publications

Jaana Rysä

4 joint publications

Outi Kummu

2 joint publications

Mikko Karpale