Hannah Maple

11PUBLICATIONS
30CO-AUTHORS
Data visualisation and computational (incl. parametric and generative) designMolecular targetsBiomolecular modelling and designIndustrial molecular engineering of nucleic acids and proteinsProteins and peptides
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Publications (11)

|Apr 17, 2025
Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse.

Anthony K Edmonds, Dimitrios-Ilias Balourdas, Graham P Marsh

|Mar 17, 2025
Development of p300-targeting degraders with enhanced selectivity and onset of degradation.

Graham P Marsh, Mark S Cooper, Sean Goggins

|Jan 16, 2025
Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease.

Ravi Kumar Akula, Haifa El Kilani, Alina Metzen

|Jan 15, 2025
Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs.

Marisa Actis, Joel Cresser-Brown, Elizabeth A Caine

|Oct 06, 2023
Efficient, multi-hundred-gram scale access to E3 ubiquitin ligase ligands for degrader development.

Mark S Cooper, Mark C Norley, Simon Armitage

|Oct 06, 2023
Chirality: a key parameter in chemical probes.

Andrew McGown, Jordan Nafie, Mohammed Otayfah

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Frequent Collaborators

9 joint publications

Graham P Marsh

3 joint publications

Robert Felix

3 joint publications

John Spencer

2 joint publications

Darko Bosnakovski