Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Adam V Patterson

12PUBLICATIONS

38CO-AUTHORS

Haematological tumoursNanophotonicsMolecular targetsWastewater treatment processesCancer therapy (excl. chemotherapy and radiation therapy)

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (12)

Sort by Publication Date:

|Nov 06, 2024

The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia.

Cara E Toscan, Hannah McCalmont, Amir Ashoorzadeh

|Jun 27, 2024

Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623.

Abigail V Sharrock, Jeff S Mumm, Elsie M Williams

|Feb 26, 2022

Interrogation of the Structure-Activity Relationship of a Lipophilic Nitroaromatic Prodrug Series Designed for Cancer Gene Therapy Applications.

Amir Ashoorzadeh, Alexandra M Mowday, Christopher P Guise

|Dec 28, 2021

Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3.

Maria R Abbattista, Amir Ashoorzadeh, Christopher P Guise

|Nov 27, 2021

Bioreductive prodrug PR-104 improves the tumour distribution and titre of the nitroreductase-armed oncolytic adenovirus ONYX-411<sup>NTR</sup> leading to therapeutic benefit.

Dean C Singleton, Alexandra M Mowday, Chris P Guise

|Oct 09, 2021

Selectively Targeting Tumor Hypoxia With the Hypoxia-Activated Prodrug CP-506.

Alexander M A van der Wiel, Victoria Jackson-Patel, Raymon Niemans

Pageof 2

Frequent Collaborators

9 joint publications

Jeff B Smaill

6 joint publications

Alexandra M Mowday

4 joint publications

David F Ackerley

2 joint publications

Amir Ashoorzadeh

2 joint publications

Victoria Jackson-Patel

2 joint publications

Zhe Fu

2 joint publications

Xiaojing Lin

1 joint publications

Yuliana Yosaatmadja

1 joint publications

Christopher J Squire

1 joint publications

Robert F Anderson

Frequent Collaborators

9 joint publications

Jeff B Smaill

6 joint publications

Alexandra M Mowday

4 joint publications

David F Ackerley

2 joint publications

Amir Ashoorzadeh

Top Related Videos

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Published on : Feb 10, 2023

Nitropeptide Profiling and Identification Illustrated by Angiotensin II

Nitropeptide Profiling and Identification Illustrated by Angiotensin II

Published on : Jun 16, 2019

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Published on : Jul 20, 2019

See more related videos

Top Related Videos

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model

Published on : Feb 10, 2023

Nitropeptide Profiling and Identification Illustrated by Angiotensin II

Nitropeptide Profiling and Identification Illustrated by Angiotensin II

Published on : Jun 16, 2019

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Published on : Jul 20, 2019

See more related videos