Thomas E Smithgall

14PUBLICATIONS
35CO-AUTHORS
Neural engineeringCheminformatics and quantitative structure-activity relationshipsAutonomic nervous systemCentral nervous systemGene and molecular therapy
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Publications (14)

|Oct 08, 2026
HIV-1 Nef Homodimerization as a Structural Mechanism for Kinase Activation and Small Molecule Inhibitor Action.

|Sep 24, 2024
Cocrystallization of the Src-Family Kinase Hck with the ATP-Site Inhibitor A-419259 Stabilizes an Extended Activation Loop Conformation.

Ari M Selzer, John J Alvarado, Thomas E Smithgall

|Aug 30, 2023
PROTAC-mediated Degradation of HIV-1 Nef Efficiently Restores Cell-surface CD4 and MHC-I Expression and Blocks HIV-1 Replication.

Lori A Emert-Sedlak, Colin M Tice, Haibin Shi

|Sep 23, 2022
Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.

Lori A Emert-Sedlak, Haibin Shi, Colin M Tice

|Sep 20, 2022
The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction.

Manish Aryal, David Lin, Kiera Regan

|Jan 06, 2022
Behavioural immune landscapes of inflammation.

Georgiana Crainiciuc, Miguel Palomino-Segura, Miguel Molina-Moreno

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Frequent Collaborators

3 joint publications

John J Alvarado

2 joint publications

Catherine E Thomas

2 joint publications

Haibin Shi

2 joint publications

Lori A Emert-Sedlak