William C Groutas

10PUBLICATIONS
12CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsProteins and peptidesPublic health nutritionMedical infection agents (incl. prions)
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Publications (10)

|Jul 02, 2024
Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies.

Chamandi S Dampalla, Yunjeong Kim, Alexandria Zabiegala

|Dec 21, 2023
Potent 3CLpro inhibitors effective against SARS-CoV-2 and MERS-CoV in animal models by therapeutic treatment.

Pengfei Li, Yunjeong Kim, Chamandi S Dampalla

|Jan 19, 2023
Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies.

Chamandi S Dampalla, Harry Nhat Nguyen, Athri D Rathnayake

|May 31, 2022
Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease.

Chamandi S Dampalla, Athri D Rathnayake, Anushka C Galasiti Kankanamalage

|Dec 06, 2021
Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.

Chamandi S Dampalla, Athri D Rathnayake, Krishani Dinali Perera

|Jul 02, 2021
Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease.

Chamandi S Dampalla, Yunjeong Kim, Naemi Bickmeier

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Frequent Collaborators

6 joint publications

Athri D Rathnayake

6 joint publications

Kevin P Battaile

5 joint publications

Chamandi S Dampalla

4 joint publications

Krishani Dinali Perera