Xiaobao Yang

10PUBLICATIONS
30CO-AUTHORS
Biomolecular modelling and designCell development, proliferation and deathHaematological tumoursMolecular targetsGene and molecular therapy
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Publications (10)

|Oct 20, 2026
Rational design and synthesis of a novel cereblon ligand class enabling selective molecular glue and potent PROTAC.

|Dec 18, 2024
Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader.

Li Chen, Yahui Zou, Renhong Sun

|Dec 05, 2024
CDK9 recruits HUWE1 to degrade RARα and offers therapeutic opportunities for cutaneous T-cell lymphoma.

Chen-Hui Luo, Li-Hong Hu, Jie-Yang Liu

|Oct 22, 2024
Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia.

Ziwei Luo, Chencen Lin, Chuwei Yu

|Nov 30, 2022
Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets.

Yan Xiong, Yue Zhong, Hyerin Yim

|Nov 22, 2022
DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs.

Fenglei Li, Qiaoyu Hu, Xianglei Zhang

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Frequent Collaborators

2 joint publications

Jian Jin

1 joint publications

Li Xia

1 joint publications

Xue-Hong Zhang

1 joint publications

Guo-Qiang Chen