Yinsheng Zhang

8PUBLICATIONS
0CO-AUTHORS
Biologically active moleculesNon-metal chemistryInstrumental methods (excl. immunological and bioassay methods)Characterisation of biological macromoleculesBiomolecular modelling and design
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Publications (8)

|Apr 16, 2020
Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor.

Baomin Liu, Kuo Gai, Hui Qin

|Mar 04, 2019
Synthesis and biological evaluation of deuterated sofosbuvir analogs as HCV NS5B inhibitors with enhanced pharmacokinetic properties.

Wangwei Ao, Xueqin Ma, Youping Lin

|Oct 31, 2018
Identification of unexpected unlabeled N,N-dimethylamide formation in the synthesis of deuterated fragment of ribociclib by a HATU-mediated coupling reaction.

Kuo Gai, Baomin Liu, Yinsheng Zhang

|Aug 18, 2018
Synthesis of deuterium-labeled crizotinib, a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

Wangwei Ao, Yuan Li, Yinsheng Zhang

|May 30, 2018
Synthesis of obeticholic acid, a farnesoid X receptor agonist, and its major metabolites labeled with deuterium.

Kuo Gai, Yu Huang, Baomin Liu

|May 18, 2018
An efficient and facile synthesis of deuterium-labeled anticancer agent bendamustine hydrochloride.

Baomin Liu, Hui Qin, Yinsheng Zhang

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