Ian James Holt

6PUBLICATIONS
46CO-AUTHORS
Medical infection agents (incl. prions)Neurology and neuromuscular diseasesMetabolic medicineMedical biochemistry - lipidsGene and molecular therapy
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (6)

|Apr 25, 2026
Mitochondrial DNA replication is regulated by endoplasmic reticulum-mitochondrial contact sites, the mitochondrial calcium uniporter, and manganese.

|Sep 16, 2024
Dysregulated FOXO1 activity drives skeletal muscle intrinsic dysfunction in amyotrophic lateral sclerosis.

Mónica Zufiría, Oihane Pikatza-Menoio, Maddi Garciandia-Arcelus

|May 08, 2024
Metabolic Malfunction Mars Muscle Mitochondria.

Guido Primiano, Ian Holt

|Jan 19, 2024
Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation.

Mikel Muñoz-Oreja, Abigail Sandoval, Ove Bruland

|Apr 28, 2022
2 deoxy-D-glucose augments the mitochondrial respiratory chain in heart.

Irati Aiestaran-Zelaia, María Jesús Sánchez-Guisado, Marina Villar-Fernandez

|Dec 07, 2021
2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA.

Boris Pantic, Daniel Ives, Mara Mennuni

Pageof 1

Frequent Collaborators

3 joint publications

Antonella Spinazzola

3 joint publications

Mikel Muñoz-Oreja

3 joint publications

Uxoa Fernandez-Pelayo

2 joint publications

Amaia Lopez de Arbina