Yan Zhang

5PUBLICATIONS
9CO-AUTHORS
Computational physiologyMolecular targetsChemical engineering designBiologically active molecules
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Journal

Publications (5)

|May 28, 2026
Discovery of a Highly Potent and Efficient BRD9 Degrader with Strong <i>In Vivo</i> Antitumor Activity.

|Mar 04, 2026
Discovery of XYD270 as a Potent, Selective, and Orally Efficacious BRD9 PROTAC for Cancer Therapy.

Yumin Huang, Guizhen Cheng, Xin Tang

|Jun 20, 2025
Discovery of a Potent, Selective, and Multiple His435 Mutation-Sensitive Thyroid Hormone Receptor β Agonist.

Qiu Li, Benqiang Yao, Shiting Zhao

|Jan 02, 2025
Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer.

Hui Shen, Hongrui Xu, Weiqin Jin

|Nov 27, 2024
Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors.

Junhua Li, Qingqing Hu, Run Zhu

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Frequent Collaborators

5 joint publications

Yong Xu

2 joint publications

Qiuping Xiang

2 joint publications

Bin Lin

2 joint publications

Junhua Li