Jonas Lategahn

9PUBLICATIONS
33CO-AUTHORS
Molecular targetsPharmacogenomicsGene and molecular therapyProteins and peptidesCheminformatics and quantitative structure-activity relationships
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Publications (9)

|Feb 26, 2024
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape.

Thomas Mühlenberg, Johanna Falkenhorst, Tom Schulz

|Jan 03, 2024
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA.

A Teuber, T Schulz, B S Fletcher

|Apr 29, 2022
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.

Jonas Lategahn, Hannah L Tumbrink, Carsten Schultz-Fademrecht

|Sep 25, 2020
Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain.

Susanne Grunewald, Lillian R Klug, Thomas Mühlenberg

|Sep 15, 2020
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.

Jonas Lategahn, Julia Hardick, Tobias Grabe

|Dec 21, 2019
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.

Jonas Lategahn, Marina Keul, Philip Klövekorn

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