Juan Luis Pacheco-García

6PUBLICATIONS
34CO-AUTHORS
Haematological tumoursReaction engineering (excl. nuclear reactions)Structure and dynamics of materialsMolecular targetsGene expression (incl. microarray and other genome-wide approaches)
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Publications (6)

|Jan 02, 2026
Targeting Oxalate Production by Combining Enzyme Inhibition and Proteolysis Activation: A Novel Therapeutic Approach for Primary Hyperoxaluria Type 1.

Fabio Arias, Sumati Rohilla, Yudibeth Sixto-López

|Jun 09, 2023
Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.

Diandra Doppler, Mukul Sonker, Ana Egatz-Gomez

|Jun 24, 2022
Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations.

Juan Luis Pacheco-Garcia, Dmitry S Loginov, Ernesto Anoz-Carbonell

|May 28, 2022
Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1.

Eduardo Salido, David J Timson, Isabel Betancor-Fernández

|Nov 24, 2021
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation.

Juan Luis Pacheco-Garcia, Dmitry Loginov, Bruno Rizzuti

|Nov 06, 2020
Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein.

Juan Luis Pacheco-García, Mario Cano-Muñoz, Isabel Sánchez-Ramos

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Frequent Collaborators

5 joint publications

Angel L Pey

2 joint publications

Dmitry S Loginov

2 joint publications

Pavla Vankova

2 joint publications

Milagros Medina