Robert H Brown

15PUBLICATIONS
132CO-AUTHORS
Gene and molecular therapyDevelopmental genetics (incl. sex determination)Medical infection agents (incl. prions)Epigenetics (incl. genome methylation and epigenomics)Gene expression (incl. microarray and other genome-wide approaches)
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Publications (15)

|Jun 25, 2026
Intravenous administration of an engineered AAV9-gene-silencing vector suppresses human SOD1 and extends survival in an ALS mouse model.

|Jan 10, 2025
Genetic Ablation of Sarm1 Mitigates Disease Acceleration after Traumatic Brain Injury in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Elif O Dogan, Sean R Simonini, James Bouley

|Sep 26, 2023
Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo.

Gabriela Toro Cabrera, Katharina E Meijboom, Abbas Abdallah

|Nov 13, 2022
The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration.

Sarah Opie-Martin, Alfredo Iacoangeli, Simon D Topp

|Oct 21, 2022
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro.

Katharina E Meijboom, Abbas Abdallah, Nicholas P Fordham

|May 19, 2022
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD.

Gopinath Krishnan, Denitza Raitcheva, Daniel Bartlett

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Frequent Collaborators

5 joint publications

Jan H Veldink

5 joint publications

Ammar Al-Chalabi

5 joint publications

Philip Van Damme

5 joint publications

Ahmad Al-Khleifat