Keefe T Chan

9PUBLICATIONS
50CO-AUTHORS
Molecular targetsGenome structure and regulationHaematological tumoursCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (9)

|Aug 12, 2026
Rb-driven transcription limits its tumour-suppressive effects in breast cancer.

|Jul 23, 2026
RAD54L coordinates the nucleolar DNA damage response to maintain rDNA stability.

|Sep 25, 2025
Exploiting dysregulated iron homeostasis to eradicate persistent high-grade serous ovarian cancer.

Carmelo Cerra, Madeleine R C Tancock, Niko Thio

|Dec 04, 2023
INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors.

Catherine Dietrich, Alec Trub, Antonio Ahn

|Jun 27, 2022
Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation.

Haoran Zhu, Keefe T Chan, Xinran Huang

|Nov 11, 2020
The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.

Shunfei Yan, Jiachen Xuan, Natalie Brajanovski

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Frequent Collaborators

6 joint publications

Richard B Pearson

4 joint publications

Elaine Sanij

3 joint publications

Ross D Hannan

3 joint publications

Anna S Trigos