Duncan Sproul

14PUBLICATIONS
92CO-AUTHORS
Predictive and prognostic markersCancer diagnosisNanoscale characterisationEpigenetics (incl. genome methylation and epigenomics)Medical molecular engineering of nucleic acids and proteins
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Publications (14)

|Apr 02, 2026
DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A.

Ioannis Kafetzopoulos, Francesca Taglini, Moira Pasquier

|Aug 25, 2025
Replication-associated mechanisms contribute to an increased CpG > TpG mutation burden in mismatch repair-deficient cancers.

Joseph C Ward, Ignacio Soriano, Steve Thorn

|Nov 11, 2024
The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment.

Hannah Wapenaar, Gillian Clifford, Willow Rolls

|Oct 24, 2024
Using human disease mutations to understand de novo DNA methyltransferase function.

Willow Rolls, Marcus D Wilson, Duncan Sproul

|Jan 30, 2024
DNMT3B PWWP mutations cause hypermethylation of heterochromatin.

|Oct 02, 2023
Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin that reflect nucleosome organisation.

Lyndsay Kerr, Ioannis Kafetzopoulos, Ramon Grima

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Frequent Collaborators

4 joint publications

Ioannis Kafetzopoulos

3 joint publications

Lyndsay Kerr

3 joint publications

Willow Rolls

3 joint publications

Marcus D Wilson