Zhiyi Yu

8PUBLICATIONS
9CO-AUTHORS
Molecular targetsCharacterisation of biological macromoleculesHaematological tumoursBiologically active molecules
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Publications (8)

|Jun 09, 2026
SHP2 Inhibition Reveals Compensatory PI3K-AKT Activation in KRAS-Driven Pancreatic Cancer: Discovery of SDUY104 and Rational Approaches for Combination Therapy.

|May 14, 2026
Dual Allosteric Targeting of SHP2: Development of Bivalent Inhibitors with Enhanced Potency for Cancer Treatment.

|Aug 11, 2025
Discovery of Novel Antiepileptic Agents Targeting the α1β2γ2 GABAA Receptor.

Yuan Gao, Amina Noraddin, Xinyi Li

|Mar 22, 2025
Increased NaV1.2 expression and its interaction with CaM contribute to the hyperexcitability induced by prolonged inhibition of CaMKII.

Hongyue Liang, Ling Qin, Rui Feng

|Jul 27, 2024
Design, Synthesis and Antitumor Activity of a Novel Class of SHP2 Allosteric Inhibitors with a Furanyl Amide-Based Scaffold.

Chengchun Zhu, Haiyang Zhao, Wenting Yang

|Jun 22, 2022
Expanded Application of a Photoaffinity Probe to Study Epidermal Growth Factor Receptor Tyrosine Kinase with Functional Activity.

Hui Deng, Qian Lei, Na Yang

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Frequent Collaborators

1 joint publications

Hui Deng

1 joint publications

Weimin Li

1 joint publications

Peng R Chen

1 joint publications

Yan Zhang