Brian C Smith

25PUBLICATIONS
47CO-AUTHORS
Epigenetics (incl. genome methylation and epigenomics)Predictive and prognostic markersMolecular targetsMedical molecular engineering of nucleic acids and proteinsInnate immunity
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Publications (25)

|Sep 28, 2026
Deep phenotyping of EHMT1 ankyrin repeat domain missense variants in Kleefstra syndrome by multi-tiered structural genomics analyses at atomic resolution.

|Aug 06, 2026
Structural Genomics Defines PBRM1 Bromodomain Variant Function in ccRCC.

|Jul 17, 2026
TAOK3 inhibition constrains invasion, potentiates paclitaxel, and reprograms the tumor microenvironment toward anti-tumor immunity in cervical cancer.

|May 22, 2026
Mitochondria-targeted metformin analogs activate the ER stress-unfolded protein response pathway to drive apoptosis in pancreatic cancer.

|Oct 15, 2025
Polybromo‑1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket.

Raymundo Nuñez, Karina L Bursch, Savannah J Makowski

|Nov 18, 2024
The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation.

Raymundo Nuñez, Paul F W Sidlowski, Erica A Steen

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Frequent Collaborators

4 joint publications

Raymundo Nuñez

3 joint publications

Sarah L Wynia-Smith

3 joint publications

Brian F Volkman

3 joint publications

John A Auchampach