W Michael Seganish

7PUBLICATIONS
21CO-AUTHORS
PharmacogenomicsGlycoconjugatesCancer therapy (excl. chemotherapy and radiation therapy)Molecular targetsMolecular medicine
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Journal

Publications (7)

|Jul 14, 2026
Discovery of Biased Dual-Agonists of Glucagon-Like Peptide 1 and Glucagon Receptors through Mutation of a Conserved Aspartate.

|Apr 30, 2026
Design of Novel Exatecan-Amide Linker-Payloads for the Development of Stable, Low-Aggregating, and Highly Efficacious Antibody-Drug Conjugates.

|Apr 30, 2026
Discovery of Novel N-Linked Camptothecin Linker-Payloads to Access Antibody-Drug Conjugates with High Target-Mediated In Vivo Efficacy.

|Sep 05, 2024
Discovery and Evaluation of TLR-Targeted Immune Agonists.

Natalia Chernyak, Bhagyashree Bhagwat, Saraswathi Naravula

|Aug 22, 2024
Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists as Novel Antibody-Drug Conjugate Payloads.

Akash M Patel, Aarron Willingham, Alan C Cheng

|Jul 25, 2022
Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1α.

Victor W Mak, Akash M Patel, Rose Yen

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Frequent Collaborators

3 joint publications

Simon B Lang

2 joint publications

Bernhard H Geierstanger

2 joint publications

Rebecca E Johnson

2 joint publications

Alan C Cheng