Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Bruno Ghirotto

6PUBLICATIONS

52CO-AUTHORS

Neurology and neuromuscular diseasesImmunogenetics (incl. genetic immunology)Medical biochemistry - amino acids and metabolitesMedical infection agents (incl. prions)Aged health care

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (6)

Sort by Publication Date:

|Apr 01, 2026

TNF alpha unmasks enteric malate aspartate shuttle dysfunction bridging Parkinson disease and intestinal inflammation.

Bruno Ghirotto, Luís Eduardo Gonçalves, Vivien Ruder

|Apr 08, 2025

TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson's Disease patients.

Bruno Ghirotto, Luís Eduardo Gonçalves, Vivien Ruder

|Oct 18, 2024

Sirtuin 1 regulates the phenotype and functions of dendritic cells through Ido1 pathway in obesity.

Jean de Lima, Jefferson Antônio Leite, Paulo José Basso

|Feb 28, 2022

MS-Driven Metabolic Alterations Are Recapitulated in iPSC-Derived Astrocytes.

Bruno Ghirotto, Danyllo F Oliveira, Marcella Cipelli

|Jul 15, 2021

Loss of mTORC2 Activity in Neutrophils Impairs Fusion of Granules and Affects Cellular Metabolism Favoring Increased Bacterial Burden in Sepsis.

Cristiane Naffah de Souza Breda, Leandro Carvalho Dantas Breda, Larissa Anastácio da Costa Carvalho

|May 24, 2021

Sirtuins as pharmacological targets in neurodegenerative and neuropsychiatric disorders.

Jefferson A Leite, Bruno Ghirotto, Vitor P Targhetta

Pageof 1

Frequent Collaborators

4 joint publications

Niels Olsen Saraiva Câmara

2 joint publications

Jefferson Antônio Leite

2 joint publications

Beate Winner

2 joint publications

Jean de Lima

2 joint publications

Cristiane Naffah de Souza Breda

2 joint publications

Juan Atilio Gerez

2 joint publications

Paulo José Basso

2 joint publications

Christina James

2 joint publications

Vivien Ruder

2 joint publications

Eloisa Martins da Silva

Frequent Collaborators

4 joint publications

Niels Olsen Saraiva Câmara

2 joint publications

Jefferson Antônio Leite

2 joint publications

Beate Winner

2 joint publications

Jean de Lima

Top Related Videos

MALDI Imaging Mass Spectrometry of Neuropeptides in Parkinson's Disease

MALDI Imaging Mass Spectrometry of Neuropeptides in Parkinson's Disease

Published on : Feb 14, 2012

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Published on : Jan 07, 2014

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function

Published on : May 04, 2021

See more related videos

Top Related Videos

MALDI Imaging Mass Spectrometry of Neuropeptides in Parkinson's Disease

MALDI Imaging Mass Spectrometry of Neuropeptides in Parkinson's Disease

Published on : Feb 14, 2012

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Published on : Jan 07, 2014

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function

Published on : May 04, 2021

See more related videos