Václav Němec

6PUBLICATIONS
23CO-AUTHORS
Separation technologiesProteins and peptidesCharacterisation of biological macromoleculesBiologically active moleculesGlycoconjugates
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Publications (6)

|Sep 10, 2025
Discovery of an exquisitely selective WDR5 chemical probe accelerated by a high-quality DEL-ML Hit.

Lasse Hoffmann, Christopher Lenz, Frederic Farges

|Feb 11, 2025
Workflow for E3 Ligase Ligand Validation for PROTAC Development.

Nebojša Miletić, Janik Weckesser, Thorsten Mosler

|Dec 27, 2024
Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε.

Adrian Haag, Václav Němec, Pavlína Janovská

|Jul 18, 2024
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2.

Václav Němec, Marek Remeš, Petr Beňovský

|Jun 27, 2024
A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7.

Christian J Muñoz Sosa, Christopher Lenz, Anton Hamann

|Aug 25, 2022
PROTAC degraders as chemical probes for studying target biology and target validation.

Václav Němec, Martin P Schwalm, Susanne Müller

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