Hiroshi Morioka

8PUBLICATIONS
4CO-AUTHORS
Molecular targetsApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Biomolecular modelling and designGeospatial information systems and geospatial data modellingOptical properties of materials
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Publications (8)

|Jun 25, 2026
Multiple binding modes of the tyrosine kinase inhibitor dovitinib to fibroblast growth factor receptor 1 characterized by surface plasmon resonance, 19F-NMR, and molecular dynamics simulations.

|Mar 11, 2026
Improving purity and apparent thermal stability of single-chain Fv antibodies by heat treatment in a soluble E. coli cytoplasmic expression system.

Sai De, Yoshihiro Kobashigawa, Kyo Okazaki

|Jan 20, 2026
Structure-based design and biophysical characterization of the linker sequence that associate to the VH-VL domain interface of the single-chain Fv antibody to suppress oligomerization propensity.

Kyo Okazaki, Yoshihiro Kobashigawa, Hiroyuki Kumeta

|Mar 12, 2024
Structure-based design, biophysical characterization, and biochemical application of the heterodimeric affinity purification tag based on the Schistosoma japonicum glutathione-S-transferase (SjGST) homodimer.

Yan Du, Yoshihiro Kobashigawa, Kyo Okazaki

|Jul 03, 2023
Molecular Dynamics-Based Design and Biophysical Evaluation of Thermostable Single-Chain Fv Antibody Mutants Derived from Pharmaceutical Antibodies.

Kyo Okazaki, Yoshihiro Kobashigawa, Hikari Morita

|Jun 29, 2021
Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogues.

Yoshihiro Kobashigawa, Toshiya Ohara, Kosuke Morita

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Frequent Collaborators

1 joint publications

Yuko Sato

1 joint publications

Hiroshi Kimura

1 joint publications

Takao Arimori

1 joint publications

Yoshihiro Kobashigawa