Sanghwa Lee

8PUBLICATIONS
6CO-AUTHORS
Molecular imaging (incl. electron microscopy and neutron diffraction)Instrumental methods (excl. immunological and bioassay methods)BioassaysPhotonics, optoelectronics and optical communicationsMechanobiology
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Publications (8)

|Oct 23, 2024
Effects of steric hindrance from single-stranded overhangs on target-strand loading into the Cas12a active site.

Heyjin Son, Youngjae Kang, Yo Han Song

|Jan 19, 2022
Exploring the dynamic nature of divalent metal ions involved in DNA cleavage by CRISPR-Cas12a.

Heyjin Son, Jaeil Park, You Hee Choi

|Dec 02, 2021
Mg2+-dependent conformational rearrangements of CRISPR-Cas12a R-loop complex are mandatory for complete double-stranded DNA cleavage.

Heyjin Son, Jaeil Park, Injoo Hwang

|Jul 17, 2020
Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly.

Sanghwa Lee, Jonghyeok Shin, Younghun Jung

|Jul 19, 2018
Direct observation of DNA target searching and cleavage by CRISPR-Cas12a.

Yongmoon Jeon, You Hee Choi, Yunsu Jang

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